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EC number: 206-354-4
CAS number: 330-54-1
reliable Guinea Pig Maximisation Test (GPMT) test was conducted in
compliance with OECD Guideline 406 on Diuron. Female guinea-pigs were
intradermally and epicutaneo
induced before being challenged with a 50% Diuron solution in saline. No
skin reaction on the basis of erythema and oedema (sensitization rate
0%) was observed. A 50% solution of Diuron did not provoke skin
sensitization (Sharp 1997).
sensitisation study was performed according to the Magnusson-Kligman
method using Freund’s complete adjuvant technique to evaluate the
sensitisation potential of test item Diuron Technical.
mean of the scores were 0.10 and 0.00 according to the 24th and 48th
hour observations. In the control group the mean of the scores were 0.10
and 0.00.Since the reactions in the test group did not markedly exceed
in the control group, no evidence of delayed contact hypersensitivity
was found in this assay
available data on sensitisation is conclusive but not sufficient for
classification according to directives DSD (67/548/EEC) or CLP
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