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EC number: 206-354-4
CAS number: 330-54-1
with column 2 of Annex IX, the study need not be conducted if the logPow
is <3. Due to the low logPow (2.89), an accumulation in aquatic
organisms is not expected. Thus, and for reasons of animal welfare, no
study on bioaccumulation in fish is performed.
Considering the log Kow of
2.89, the BCF for fish can be calculated according to the equation 74 of
the TGD as follows:
logBCFfish = 0.85
*· logKow – 0.70
·* 2.89 – 0.7
=> BCFfish = 57.1
A BCF of 57.1
confirms the low potential of Diuron to accumulate in the aquatic food
chain. Experimental data are not considered necessary.
However, a GLP
Guideline study is available for this substance, modified for use withMytilus
edulis. The calculated BCF of 5.2 confirms the low potential for
Diuron to bioaccumulate.
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