Registration Dossier

Physical & Chemical properties

Solubility in organic solvents / fat solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

According to “ANNEX IX- STANDARD INFORMATION REQUIREMENTS FOR SUBSTANCES MANUFACTURED OR IMPORTED IN QUANTITIES OF 100 TONNES OR MORE, study for Stability in organic solvents and identity of relevant degradation products is only required if stability of the substance is considered to be critical.
But one reliable report source is available and report that the substance is stable but the substance is very soluble in organic solvents as ethanol and methanol and therefore is not stable in organic solvents as ethanol and methanol and stable in other organic solvents.
[Lide, D.R., G.W.A. Milne (eds.). Handbook of Data on Organic Compounds. Volume I. 3rd ed. CRC Press, Inc. Boca Raton ,FL. 1994., p. V3: 2674
The substance is from Glycol Ethers Category: Its functional groups indicate no solubility in common organic solvents. Solubility in organic solvents is not considered critical. (Ref. 1)
Therefore testing for solubility in organic solvents does not need to be performed.

Ref. 1) European Chemicals Agency (ECHA), Guidance for the implementation of REACH, Guidance on information requirements and chemical safety assessment, Chapter R.7a: Endpoint specific guidance, May 2008, pages 168-171.

Key value for chemical safety assessment

Additional information

According to “ANNEX IX- STANDARD INFORMATION REQUIREMENTS FOR SUBSTANCES MANUFACTURED OR IMPORTED IN QUANTITIES OF 100 TONNES OR MORE, study for Stability in organic solvents and identity of relevant degradation products is only required if stability of the substance is considered to be critical.

But one reliable report source is available and report that the substance is stable but the substance is very soluble in organic solvents as ethanol and methanol and therefore is not stable in organic solvents as ethanol and methanol and stable in other organic solvents.

[Lide, D.R., G.W.A. Milne (eds.). Handbook of Data on Organic Compounds. Volume I. 3rd ed. CRC Press, Inc. Boca Raton ,FL. 1994., p. V3: 2674

The substance is from Glycol Ethers Category: Its functional groups indicate no solubility in common organic solvents. Solubility in organic solvents is not considered critical. (Ref. 1)

Therefore testing for solubility in organic solvents does not need to be performed.

Ref. 1) European Chemicals Agency (ECHA), Guidance for the implementation of REACH, Guidance on information requirements and chemical safety assessment, Chapter R.7a: Endpoint specific guidance, May 2008, pages 168-171.