Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information


When released to water, some studies show that biodegradation of category members is reasonably rapid (Table 2). OECD guideline studies indicate biodegradability (> 90%) for TGBE ((Triethylene glycol monobutyl ether's or (2-(2-(2-butoxyethoxy)ethoxy)ethanol)).

However, the APHA comparative biodegradation study of TGBE indicate slower rates of biodegradation (from 47-71%). Altogether, the data suggest that different study methodologies provide variable results for the tri- and tetraethylene glycol ethers.

No category members or surrogates that were tested demonstrate marked resistance to biodegradative processes.

Due to the structural and physical similarities with the other glycol ethers in the category, TetraBE is likely to be biodegradable.

Table 2 Comparison of Biodegradation Rate Ranges for Category Members and Surrogates

Category Member

Biodegradation Rate Ranges



47% after 20 days (APHA) (ready) 88% after 14 day (OECD) (ready) 92% after 21 days (OECD) (ready)** 100% after 9 days (OECD) (inherent)

TetraME 23783-42-8

99% after 8 days (OECD) (inherent)**

TetraBE 1559-34-8

Data for all chemicals are used

TGME 112-35-6

71% after 20 days (APHA) (inherent)

TGEE 112-50-5

71% after 20 days (APHA) (inherent)

MPEG 350 9004-74-4

No data

DOT4 Brake Fluid

No data

Polyethylene glycol monobutyl ether 9004-77-7

No data