Registration Dossier

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only secondary source available. No data on test protocol, resulting LD50 only.

Data source

Reference
Reference Type:
secondary source
Title:
Toxicological Evaluations 12 - Potential Health Hazards of Existing Chemicals.
Author:
BG Chemie
Bibliographic source:
Toxicological Evaluations, volume 12, section "N,N'-di-sec-butyl-p-phenylenediamine", p. 193-203. Published by Springer.

Materials and methods

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rat
Strain:
Wistar
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 10 - < 50 mg/kg bw
Based on:
test mat.
Clinical signs:
reeling, dyspnoea, poor general condition
Gross pathology:
intra-abdominal adhesions

Applicant's summary and conclusion