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Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1976
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Very concise test report, no information on test protocol available.
Justification for type of information:
No study was selected since weight of evidence approach was applied.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1976
Report Date:
1976

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Inhalation toxiticy test with an exposure of 6 hours.
GLP compliance:
no
Remarks:
Study performed in 1976
Test type:
other: no data
Limit test:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name: Santoflex 44
- Lot n°: 274777

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
male

Administration / exposure

Route of administration:
inhalation
Type of inhalation exposure:
not specified
Vehicle:
not specified
Details on inhalation exposure:
Sample temperature: ambient
Chamber temperature: 27°C
Chamber humidity: 80%
Chamber volume: 35L
Air flow rate: 4.0 L/min

Initial sample: 69.1 g
Recovered sample: 68.7 g
Condensed sample: 0.0 g
Vaporized sample: 0.4 g
Analytical verification of test atmosphere concentrations:
not specified
Duration of exposure:
6 h
Concentrations:
0.2 mg/L
No. of animals per sex per dose:
6 males
Control animals:
not specified

Results and discussion

Effect levels
Sex:
male
Dose descriptor:
LC50
Effect level:
> 0.2 mg/L air
Based on:
test mat.
Exp. duration:
6 h
Mortality:
no mortalities
Clinical signs:
no toxic signs
Other findings:
Viscera appeared normal in survivors (14d).

Applicant's summary and conclusion