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EC number: 239-701-3
CAS number: 15625-89-5
Table 1: Number of observed mortalities:
A study was conducted to evaluate the acute
dermal toxicity of the test substance (trimethylolpropane triacrylate -
TMPTA) in rabbits.
Sixteen albino rabbits were prepared by
careful removal of the hair with electric clippers. Planned areas of
application were identified and in half of the animals the area was
lightly abraded. After weighing the animal, the calculated dose was
applied and the entire area covered with a rubber dam, held in place by
tape. The dose levels applied were 0.315, 0.795, 1.99 and 5.0 mL/kg bw the
test substance (trimethylolpropane triacrylate - TMPTA).
One mortality was observed at dose levels
1.99 and 5.0 mL/kg bw. In some cases, the test substance
(trimethylolpropane triacrylate - TMPTA)
In conclusion, the single dermal median
lethal dose (LD50) of the test substance (trimethylolpropane triacrylate
- TMPTA) was determined to be 4.7 mL/kg bw (i.e. 5170 mg/kg bw) in
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