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EC number: 239-701-3
CAS number: 15625-89-5
of mortality data
study was conducted to assess the single dose toxicity of the test
substance (trimethylolpropane triacrylate - TMPTA) in Sprague-Dawley
rats using the standard acute method.
of 5 Sprague-Dawley
rats/dose (sex unspecified) received a single oral (gavage) dose of 50.0,
127.5, 315.1, 785, 1999, 5000 mg/kg. The test substance
(trimethylolpropane triacrylate - TMPTA). The
three lower doses were administered as 10% suspensions stabilized by the
incorporation of 5% acacia, while the three higher doses were
administered undiluted. Parameters evaluated included survival and clinical
observations on the day of dosing and at least daily thereafter for 14
mortalities were observed except in two of the five animals in the 5000
mg/kg bw group.
conclusion, the single oral median lethal dose (LD50) of the test
substance (trimethylolpropane triacrylate - TMPTA) in rats was
calculated to be >5000 mg/kg bw.
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