Registration Dossier
Registration Dossier
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EC number: 208-288-1 | CAS number: 520-26-3
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
At neutral pH (pH 7.4 in experiment) hesperidin is stable towards hydrolysis (DT50 > 60 days at 25 and 40 °C). At pH 9 DT50 of hesperidin is 23 days at 25 °C and 4.5 days at 40 °C.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 60 d
- at the temperature of:
- 40 °C
Additional information
Hesperidin is stable in acidic and neutral pH conditions but undergoes hydrolysis at alkaline conditions. The difference shown between 25 °C and 40 °C shows that higher temperature enhances hydrolysis.
Half-life at pH 1.2, 3, 5 and 7.4 are >60 days (at 25 and 40 °C) whereas at pH 9 hydrolysis is observed resulting in a half-life of 23 days at 25 °C and 4.5 days at 40 °C.
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