Registration Dossier
Registration Dossier
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EC number: 208-288-1 | CAS number: 520-26-3
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Hesperidin has been tested for biodegradability and bioaccumulation potential (logPOW) and has shown not to fulfill the screening criteria for p/vP resp. B/vB criteria. No toxicity to men is known for hesperidin, neither by CMR properties nor by sub-chronic toxicity. Acute aquatic toxicity also is not of concern.
- Likely routes of exposure:
Likely routes of exposure are by inhalative route during manufacturing and use as intermediate, as hesperidin usually is handled as a fine brownish powder with a low particle size. In addition the oral route is relevant, as hesperidin is mainly used as pharmaceutical intermediate and food/nutrition supplement.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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