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EC number: 203-710-0
CAS number: 109-83-1
The data refer to the charged molecule.
The pH corrected partition coefficients for
the ionisable substance N-Methylethanolamine was calculated for pH 4 to
be 9.18E-11 Pa*m³/mol, for pH 5 to be 9.18E-10 Pa*m³/mol, for pH 7 to be
9.17E-8 Pa*m³/mol and for pH 9 to be 8.25E-6 Pa*m³/mol.
The key value for chemical safety assessment
is taken from the performed calculation with the computer tool EPIWIN
(Chemservice S.A., 2010, revised 2019).
From the water suirface. the substance will
not evaporate into the atmosphere.
Article 13 of Regulation (EC) No 1907/2006, it is laid down that
information on intrinsic properties of substances may be generated by
means other than tests, provided that the conditions set out in Annex
XI (of the same Regulation) are met. Furthermore, according to Article
25 of the same Regulation testing on vertebrate animals shall be
undertaken only as a last resort.
to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used
if (1) the scientific validity of the (Q)SAR model has been
established, (2) the substance falls within the applicability domain
of the (Q)SAR model, (3) the results are adequate for the purpose of
classification and labeling and/or risk assessment and (4) adequate
and reliable documentation of the applied method is provided.
the assessment of the N-Methylethanolamine
109-83-1) (Q)SAR results were used for the estimation of the Henry’s
Law constant. The criteria listed in Annex XI of Regulation (EC) No
1907/2006 are considered to be adequately fulfilled and therefore the
endpoint(s) sufficiently covered and suitable for risk assessment.
further experimental studies on the Henry’s Law Constant are not
bond estimation method gives a value of 8.18E-05 Pa*m³/mol (HENRYWIN
Program, v3.20; EPI Suite v4.10; BASF SE, 2013), which is
representative for the uncharged molecule.
substance ist within the applicability domain of the model.
environmental conditions the molecule is expected to beionised;therefore,
the estimate may overestimate the evaporation potential of the
for pH 4 to be 9.18E-11 Pa*m³/mol,
for pH 5 to be 9.18E-10 Pa*m³/mol,
for pH 7 to be 9.17E-8 Pa*m³/mol and
for pH 9 to be 8.25E-6 Pa*m³/mol.
can be concluded that the
substance will not evaporate from the water surface into the
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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