Registration Dossier
Registration Dossier
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EC number: 201-622-7 | CAS number: 85-68-7
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The NOEC of the test substance to Mysidopsis bahia is 0.075 mg/L.
Key value for chemical safety assessment
Additional information
Two studies of the chronic toxicity of benzyl butyl phthalate to Daphnia magna are available. Both are useable as key studies for the fulfilment of this endpoint.
Rhodes et al. (1995) performed a 21 day flow-through test. The NOEC, based upon mortality and reproduction of the daphnids was 0.28 mg/L (the LOEC was 1.4 mg/L).
EG&G Bionomics (1979) performed a two-generation 42 day flow through test. The NOEC, based upon mortality and reproduction of the daphnids was 0.26 mg/L. Effects were seen at the 0.76 mg/L level.
Monsanto (study number 86 -7 -2074) report the 28 day NOEC of the substance to the shrimpMysidopsis bahiais 0.075 mg/L. This relates to the reproduction of the mysids. This study has not been reviewed. However the study, and its result, are considered valid in the BBP EU RAR and has been used in this reliable document as the critical result for determining PNECs. Therefore this result will be used in the environmental assessment as it is the most sensitive chronic result for invertebrates.
Data from review articles from Staples (1997) and Gledhill (1980) reviews can be used as supporting studies. These report NOECs for Daphnia magna of 0.35 and 0.26 mg/L respectively.
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