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EC number: 201-622-7
CAS number: 85-68-7
No information was provided on the actual test concentration, other than
it being a saturated atmosphere.
Four mature male rats were placed in a small
metal chamber (50 L) and exposed (whole-body) for 6 hours to a saturated
atmosphere of Santicizer 160 vapours (created by passing a stream of
compressed air through a container of fluid inside the chamber), and
observed "frequently" for toxic symptoms for a further 3 days.
No deaths were seen during the 3-day
observation period. Breathing was slightly irregular and moderate
lethargy developed after 30 minutes (number of animals involved not
indicated in report). There was mild nasal irritation, but no observable
ocular irritation. The animals maintained their sense of balance when
moving around ("further indication that the fumes were not particularly
harmful to the rat from an acute standpoint"). The animals ate and acted
normally during the 3-day observation period.
As no deaths and only mild transient effects
were seen in rats exposed to a saturated atmosphere containing
Santicizer 160 vapours, the test material would not be classified as
acutely toxic by the inhalation route according to EU CLP regulations.
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