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EC number: 925-259-5
CAS number: 140921-24-0
The test substance was examined for its acute dermal toxicity similar to EU method B.3. Ten Wistar rats were equally divided to sex. A dose of 2000 mg/kg bw was applied. The hair was clipped from the back of each animal, the test substance was applied for 24 hours and the application site was covered with patches and aluminium foil. After an observation time of 14 days no mortality was observed. The growth of male rats was not influenced. Female animals showed a temporarily decrease or stagnation of their body weight. Systemic symptoms of poisoning and local changes on the skin were not observed. All animals that were sacrificed at the end of the study did not show any conspicuous symptoms. Thus, the deduced LD50 value is >2000 mg/kg bw.
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