Registration Dossier
Registration Dossier
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EC number: 200-018-0 | CAS number: 50-21-5
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Justification for type of information:
- For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
- Reason / purpose for cross-reference:
- read-across source
- Temp.:
- 20 °C
- Vapour pressure:
- 0.004 hPa
- Transition / decomposition:
- no
- Conclusions:
- Vapour pressure of L(+) lactic acid is estimated to be 0.0041 mbar at 20 °C.
- Executive summary:
Vapour pressure of L(+) lactic acid is estimated to be 0.0041 mbar at 20 °C.
This information is used in a read-across approach in the assessment of the target substance.
For details and justification of read-across please refer to the attached report in section 13 of IUCLID.
- Endpoint:
- vapour pressure
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Study period:
- 2008
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- QSAR prediction
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- QSAR calculation
- GLP compliance:
- no
- Type of method:
- other: QSAR
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0.029 mm Hg
- Remarks on result:
- other: equivalent to 0.038 hPa.
- Transition / decomposition:
- no
- Conclusions:
- Lactic acid was estimated to have a vapour pressure of 0.0286 mm Hg at 25 °C according to the modified Grain method, corresponding to 0.038 hPa.
- Executive summary:
Lactic acid was estimated to have a vapour pressure of 0.0286 mm Hg at 25 °C according to the modified Grain method, corresponding to 0.038 hPa.
Referenceopen allclose all
Description of key information
The vapour pressure of lactic acid at room temperature is negligble (0.038 hPa, worst case from two QSAR calculations).
Key value for chemical safety assessment
- Vapour pressure:
- 0.038 hPa
- at the temperature of:
- 25 °C
Additional information
Pure, crystalline lactic acid has an estimated vapour pressure of 0.0286 mm Hg (corresponding to 0.038 hPa.) (worst-case from two QSAR calculations). The vapour pressure of a 93% aqueous solution of lactic acid will be dominated by the vapour pressure of the water present in the solution, up to the boiling point of the solution.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
