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Physical & Chemical properties

Vapour pressure

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Endpoint:
vapour pressure
Type of information:
other: Expert statement
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Expert statement
Reference:
Composition 0
Principles of method if other than guideline:
Method: other: calculation of vapour pressure.
GLP compliance:
no
Type of method:
other: calculation
Test material information:
Composition 1
Temp.:
20 °C
Vapour pressure:
0.004 hPa
Transition / decomposition:
no
Conclusions:
Vapour pressure of L(+) lactic acid is estimated to be 0.0041 mbar at 20 °C.
Executive summary:

Vapour pressure of L(+) lactic acid is estimated to be 0.0041 mbar at 20 °C.

Endpoint:
vapour pressure
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Justification for type of information:
This information is used in a read-across approach in the assessment of the target substance.
Reason / purpose:
read-across source
Related information:
Composition 1
Reference:
Composition 0
Principles of method if other than guideline:
Method: other: calculation of vapour pressure.
GLP compliance:
no
Type of method:
other: calculation
Test material information:
Composition 1
Temp.:
20 °C
Vapour pressure:
0.004 hPa
Transition / decomposition:
no
Conclusions:
Vapour pressure of L(+) lactic acid is estimated to be 0.0041 mbar at 20 °C.
Executive summary:

Vapour pressure of L(+) lactic acid is estimated to be 0.0041 mbar at 20 °C.

This information is used in a read-across approach in the assessment of the target substance.

For details and justification of read-across please refer to the attached report in section 13 of IUCLID.

Endpoint:
vapour pressure
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
QSAR prediction
Reference:
Composition 0
Principles of method if other than guideline:
Method: other (calculated)
GLP compliance:
no
Type of method:
other: QSAR
Test material information:
Composition 1
Temp.:
20 °C
Vapour pressure:
0.029 mm Hg
Transition / decomposition:
no
Conclusions:
Lactic acid was estimated to have a vapour pressure of 0.0286 mm Hg at 25°C according to the modified Grain method.
Executive summary:

Lactic acid was estimated to have a vapour pressure of 0.0286 mm Hg at 25°C according to the modified Grain method.

Description of key information

Vapour pressure of lactic acid at room temperature is negligible. It is predicted by QSAR modelling with  0.0041 mbar at 20 °C and  0.0381 mbar at 25°C. 

Key value for chemical safety assessment

Vapour pressure:
0.41 Pa
at the temperature of:
20 °C

Additional information

Pure, crystalline lactic acid has an estimated vapour pressure of 0.02381 mbar at 25°C. The vapour pressure of a 93% aqueous solution of lactic acid will be dominated by the vapour pressure of the water present in the solution, up to the boiling point of the solution.