Lactic acid

Viscosity

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

viscosity

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

key study

Justification for type of information:

For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.

Reason / purpose for cross-reference:

read-across source

Key result

Temp.:

other: 25.0°C

Parameter:

other: cP

Value:

18.4

Remarks on result:

other: 80 % w/w solution of lactic acid

Concentration: 88.6 %. Result: 36.9 mPs at 25 °C

Conclusions:

The value found by PURAC at 80 % and 25 °C matches with the values reported in Holten (75.33 % lactic acid at 25 °C, 13.03 cP and 85.32 % at 25 °C, 28.5 cP). The values of 18.4 cP at 80 % and 25 °C and 36.9 cP at 88.6 % and 25 °C are relevant.

Executive summary:

In a PURAC internal report the viscosity of lactic acid at various concentrations and temperatures is given. Measurement is done by Übbelohde viscosimeter. Temperatures varied between 25 °C and 80 °C, concentrations between 20 and 80 %. An 80 % solution has a viscosity of 18.4 cP at 25 °C.

This information is used in a read-across approach in the assessment of the target substance. For details and justification of read-across please refer to the attached report in section 13 of IUCLID.

Reference 2

Endpoint:

viscosity

Type of information:

other: Handbook data

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Principles of method if other than guideline:

Data are reported from literature sources. No methods were specified.

GLP compliance:

no

Type of method:

other: not reported

Temp.:

other: 25.0 °C

Parameter:

dynamic viscosity (in mPa s)

Value:

36.9

Conclusions:

At 25 °C a lactic acid aqueous solution of 88.6 % w/w has a viscosity of 36.9 centipoise. Viscosity increases with increasing concentration and decreases with increasing temperature.

Executive summary:

At 25 °C a lactic acid aqueous solution of 88.6 % w/w has a viscosity of 36.9 centipoise. Viscosity increases with increasing concentration and decreases with increasing temperature.

Reference 3

Endpoint:

viscosity

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

supporting study

Justification for type of information:

For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.

Reason / purpose for cross-reference:

read-across source

Temp.:

other: 25.0 °C

Parameter:

other: cP

Value:

18.4

Remarks on result:

other: 80 % aqueous solution

Temp.:

40°C

Parameter:

other: cP

Value:

9.4

Remarks on result:

other: 80 % aqueous solution

Temp.:

other: 60.0 °C

Parameter:

other: cP

Value:

4.8

Remarks on result:

other: 80 % aqueous solution

Temp.:

other: 80.0 °C

Parameter:

other: cP

Value:

2.9

Remarks on result:

other: 80 % aqueous solution

Conclusions:

The viscosity of lactic acid 80 % solution is in line with expectations and literature data.

Executive summary:

Viscosity was determined with an Übbelohde viscosimeter. An 80 % aqueous solution of lactic acid has a viscosity of 18.4 cP (= 18.4 mPa × s) at 25 °C.

This information is used in a read-across approach in the assessment of the target substance.

For details and justification of read-across please refer to the attached report in section 13 of IUCLID.

Description of key information

An 80 % aqueous solution of lactic acid has a viscosity of 18.4 cP (= 18.4 mPa × s) at 25 °C.

At 25 °C a lactic acid aqueous solution of 88.6 % w/w has a viscosity of 36.9 centipoise. Viscosity increases with increasing concentration and decreases with increasing temperature.

Key value for chemical safety assessment

Viscosity:

18.4 mPa · s (dynamic)

at the temperature of:

25 °C