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Ecotoxicological information

Toxicity to terrestrial arthropods

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Administrative data

Endpoint:
toxicity to terrestrial arthropods: short-term
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1985

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Pesticide Assessment Guidelines. FIFRA Subdivision L, Hazard Evaluation: Insecticide and Rodenticide Act, Non-Target Insects.Environmental Protection Agency, Office of Pesticide Programs. October,1982.
GLP compliance:
no
Application method:
contact

Test material

Reference
Name:
Unnamed
Type:
Constituent

Sampling and analysis

Analytical monitoring:
not specified

Test substrate

Vehicle:
yes
Details on preparation and application of test substrate:
Vehicle: water

Test organisms

Test organisms (species):
Apis mellifera
Animal group:
Hymenoptera (honeybees)
Details on test organisms:
TEST ORGANISM
- Common name: Honeybee
- Source: Own breed of the test facility
- Age at test initiation (mean and range, SD): < 3 weeks
- Weight at test initiation (mean and range, SD): No data
- Date of collection: No data
- Cultural background (if honeybees): No data
- Disease free: No data
- Kept according to standard practices: Yesm according to "Bee Keeping in Maryland," Cooperative Extension Services, University of Maryland, Bulletin 223, 1977.

ACCLIMATION
- Acclimation period: No data
- Acclimation conditions (same as test or not): No data
- Feeding: No data
- Health during acclimation (any mortality observed): No data

Study design

Study type:
laboratory study
Limit test:
no
Remarks:
Single dosing
Post exposure observation period:
48 hours

Test conditions

Test temperature:
No data
pH (if soil or dung study):
Not applicable
Humidity:
No data
Photoperiod and lighting:
No data
Nominal and measured concentrations:
6.9, 12.8, 25.1, 50.2, and 100.4 µg/bee (nominal)

Results and discussion

Effect concentrations
Duration:
48 h
Dose descriptor:
LD50
Effect conc.:
> 100.4 µg per animal
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The contact LD50 value of SY-83 (L-(+)-lactic acid) in the honey bee was determined to be greater than 100.4 µg/bee, the highest concentration tested.
Executive summary:

Mortality rates in all five treatment groups were similar to those observed in the control and solvent control groups. Mortalities did not appear to be treatment related.

In conclusion, SY-83 was classified as relatively non-toxic to honey bees. The 48 hour contact LD50 value for SY-83 to honey bees was greater than 100.4 µg/bee, the highest dosage tested.