Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 235-227-6
CAS number: 12136-45-7
Potassium Hydroxide (0.1%) does not induce cutaneous sensitization in
When Potassium oxide is hydrated is produced Potassium hydroxide.
Therefore, the health effects of Potassium hydroxide need to be
considered in the assessment of Potassium oxide.
No evidence of sensitisation in the study of Johnson GT et al.1975.The
test substance (Potassium hydroxide as a surrogate for
Potassium oxide) is not sensitising to skin.
Potassium Hydroxide (0.1%) does not induce cutaneous
sensitization in guinea pigs. This result can be reliably be read across
to the substance Potassium oxide l (CAS# 12136-45-7 )
There are no Respiratory sensitisationstudies
Due to the absence of chemical groups or other structural alerts
this substance is not considered to exhibit an high hazard potential.
Potassium oxide is of low priority for further work based on a low
hazard potential.is of low priority for further work based on a low
Based on the hazard assessment of Potassium
oxide/Dipotassium oxide section 2.1 and
2.2. in IUCLID 5.4., available data for the substance and following the
“Guidance on Information Requirement and Chemical Safety Assessment R.8.
Characterisation of dose [concentration]- response for human health”
andaccording to the criteria described in Directive 67/548 and in the
Respiratory Sensitisation Xn
R42 May cause sensitization by inhalation
Respiratory Irritation Xi
R37 irritating to respiratory system
H334 Resp. Sens. 1 May cause allergy or asthma symptoms or breath-ing difficulties if inhaled
H335 STOT SE 3 May cause respiratory irritation
It is concluded that the substance Potassium
oxide/Dipotassium oxide does notmeet the
criteria to be classified for human health hazards for Inhalation -
local effect: respiratory sensitisation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again