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Ecotoxicological information

Toxicity to terrestrial plants

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Endpoint:
toxicity to terrestrial plants: long-term
Data waiving:
other justification
Justification for data waiving:
other:
Endpoint:
toxicity to terrestrial plants: long-term
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: US EPA accepted QSAR method for chemicals properties assessment.
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6
Qualifier:
according to
Guideline:
other: QSAR
Principles of method if other than guideline:
EPI Suite v 4.1/ECOSARv1.00
GLP compliance:
no
Remarks:
not applicable. QSAR model
Analytical monitoring:
not required
Vehicle:
no
Species:
other: Terrestrial plants,QSAR model
Plant group:
other: QSAR model
Details on test organisms:
no further information
Test type:
other: QSAR
Study type:
other: QSAR
Substrate type:
other: QSAR
Limit test:
no
Total exposure duration:
30 d
Test temperature:
not applicable. QSAR model
pH:
not applicable. QSAR model
Moisture:
not applicable. QSAR model
Details on test conditions:
-Name of test material (as cited in study report:Potassium oxide
CAS Number: 12136-45-7
SMILES : KOK
CHEM : Potash (potassium oxide)
MOL FOR: O1 K2
MOL WT : 94.20
Values used to Generate ECOSAR Profile

Log Kow: -1.380 (EPISuite Kowwin v1.68 Estimate)
Wat Sol: 1E+006 (mg/L, EPISuite WSKowwin v1.43 Estimate)

Reference substance (positive control):
no
Species:
other: Terrestrial plants,QSAR model
Duration:
96 h
Dose descriptor:
EC50
Effect conc.:
1 368.296 mg/kg soil dw
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
not specified
Remarks on result:
other: 1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
Species:
other: Terrestrial plants,QSAR model
Duration:
30 d
Dose descriptor:
NOEC
Effect conc.:
178.832 mg/kg soil dw
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
not specified
Remarks on result:
other: cited as a ChV value, 1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
Details on results:
The ECOSAR QSAR model predicts that 30-day, NOEC cited as a ChV value would to be 178.832 mg/L (ppm) for terrestrial plants.
The ECOSAR QSAR model predicts that 96-hr EC50 valuewould to be 1368.296mg/L (ppm) for terrestrial plants.
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.

Overview of QSARs estimations on toxicity of  Dipotassium oxide/Potassium oxide to terrestrial plants 

Method

 

Results

Remarks

Reference

QSAR

estimate

Terrestrial plants ,96-hrEC50 = 1368.296 mg/L (ppm)

 Terrestrial plants, 30-day, ChV (chronic value) =178.832 mg/L (ppm)

 

 

Reliable with restrictions,

QSAR estimated data

ECOSAR Program (v1.00)

 

Terrestrial plants ,96-hrEC50 = 1368.296 mg/L (ppm)

Terrestrial plants, 30-day, ChV (chronic value) =178.832 mg/L (ppm)

1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.

Validity criteria fulfilled:
yes
Remarks:
US EPA accepted QSAR method for chemicals properties assessment.
Conclusions:
The ECOSAR QSAR model predicts that 30-day, NOEC cited as a ChV value would to be 178.832 mg/L (ppm) for terrestrial plants.
The ECOSAR QSAR model predicts that 96-hr EC50 value would to be 1368.296 mg/L (ppm) for terrestrial plants.
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
Executive summary:

The ECOSAR QSAR model predicts that 30-day, NOEC cited as a ChV value would to be 178.832 mg/L (ppm) for terrestrial plants.

The ECOSAR QSAR model predicts that 96-hr EC50 value would to be 1368.296 mg/L (ppm) for terrestrial plants.

1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.

Description of key information

The ECOSAR QSAR model predicts that 30-day, NOEC cited as a ChV value would to be 178.832 mg/L (ppm) for terrestrial plants.
The ECOSAR QSAR model predicts that 96-hr EC50 value would to be 1368.296 mg/L (ppm) for terrestrial plants.
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.

Key value for chemical safety assessment

Short-term EC50 or LC50 for terrestrial plants:
1 368.296 mg/kg soil dw
Long-term EC10, LC10 or NOEC for terrestrial plants:
178.832 mg/kg soil dw

Additional information

The ECOSAR QSAR model predicts that 30-day, NOEC cited as a ChV value would to be 178.832 mg/L (ppm) for terrestrial plants.

The ECOSAR QSAR model predicts that 96-hr EC50 value would to be 1368.296 mg/L (ppm) for terrestrial plants.

1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.