Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

In a guideline (OECD 406) and GLP study, acetonitrile was found to be non-sensitizing to guinea pig skin when tested by the Buehler method (Hill Top Research, 1997).


Migrated from Short description of key information:
Negative results were obtained in a reliable guinea pig study.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

Acetonitrile is not a skin sensitizer in guinea pigs based on reliable data. No classification is proposed for skin sensitisation based on the data available.