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Environmental fate & pathways

Biodegradation in soil

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Endpoint:
biodegradation in soil
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Remarks:
Limited information available
Principles of method if other than guideline:
Estimated from data on aqueous aerobic biodegradation
Test type:
not specified
DT50:
> 168 - < 672 h
Remarks on result:
other: Estimated

A half-life range in soil of 168 -672 hours (1 -4 weeks) has been estimated from data on aqueous aerobic biodegradation (Howard et al. 1991).

Executive summary:

A half-life range for acetonitrile in soil of 168 -672 hours (1 -4 weeks) has been estimated from data on aqueous aerobic biodegradation (Howard et al. 1991).

Endpoint:
biodegradation in soil
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Remarks:
Limited information available
Test type:
not specified

The soil bacterium Aeromonas sp. BN 7013 and soil fungus Fusarium solani also grow using acetonitrile (Harper, 1977; Kuwahara et al. 1980).

Executive summary:

The soil bacterium Aeromonas sp. BN 7013 and soil fungus Fusarium solani also grow using acetonitrile (Harper, 1977; Kuwahara et al. 1980).

Endpoint:
biodegradation in soil
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Remarks:
Limited information available. Design does not meet guidelines.
Principles of method if other than guideline:
No information available.
Test type:
not specified
Initial conc.:
10 other: mg/ml
Based on:
test mat.
% Degr.:
14
Sampling time:
3 h
% Degr.:
52
Sampling time:
8 h
DT50:
7 h
Remarks on result:
other: Nocardia rhodochrus in barnyard soil

Acetonitrile was used as the sole carbon and nitrogen source by Pseudomonas putida in soil and by Nocardia rhodochrus in barnyard soil (10 mg acetonitrile/ml); metabolites included ammonia, acetamide and acetic acid (Digeronimo and Antoine, 1976; Nawoz et al. 1989). In the study using Nocardia sp. 14% degradation occurred in 3 hours and 52% in 8 hours; the half-life was 7 hours.

Executive summary:

Acetonitirile was used as the sole carbon and nitrogen source by Pseudomonas putida in soil and by Nocardia rhodochrus in barnyard soil (10 mg acetonitrile/ml); metabolites included ammonia, acetamide and acetic acid (Digeronimo and Antoine, 1976; Nawoz et al. 1989). In the study using Nocardia sp. 14% degradation occurred in 3 hours and 52% in 8 hours; the half-life was 7 hours.

Endpoint:
biodegradation in soil: simulation testing
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance is readily biodegradable

Description of key information

In the study using Nocardia sp. 14% degradation occurred in 3 hours and 52% in 8 hours; the half-life was 7 hours.  A half-life range for acetonitrile in soil of 168 -672 hours (1 -4 weeks) has been estimated from data on aqueous aerobic biodegradation (Howard et al. 1991).   A waiver from further testing in soil is requested.

Key value for chemical safety assessment

Additional information

A half-life range for acetonitrile in soil of 168 -672 hours (1 -4 weeks) has been estimated from data on aqueous aerobic biodegradation (Howard et al. 1991).

Acetonitirile was used as the sole carbon and nitrogen source by Pseudomonas putida in soil and by Nocardia rhodochrus in barnyard soil (10 mg acetonitrile/ml); metabolites included ammonia, acetamide and acetic acid (Digeronimo and Antoine, 1976; Nawoz et al. 1989). In the study using Nocardia sp. 14% degradation occurred in 3 hours and 52% in 8 hours; the half-life was 7 hours.

The soil bacterium Aeromonas sp. BN 7013 and soil fungus Fusarium solani also grow using acetonitrile (Harper, 1977; Kuwahara et al. 1980).

A waiver from further testing in soil is requested on the basis that it is not scientifically justified because acetonitrile is readily biodegradable in reliable screening tests.