Registration Dossier

Administrative data

Endpoint:
distribution modelling
Type of information:
(Q)SAR
Remarks:
Estimated via US EPA EPIWIN software (v3.20) Level III Fugacity Model
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Remarks:
Model cited in R.7 guidance

Data source

Reference
Reference Type:
other: Modeled
Title:
US EPA EPIWIN v3.20
Author:
US EPA
Year:
2009
Bibliographic source:
US EPA EPIWIN Suite v3.20

Materials and methods

Model:
calculation according to Mackay, Level III
Calculation programme:
US EPA EPIWIN v3.20
Release year:
2 007
Media:
other: Air - Water - Soil - Sediment

Test material

Constituent 1
Chemical structure
Reference substance name:
Acetonitrile
EC Number:
200-835-2
EC Name:
Acetonitrile
Cas Number:
75-05-8
Molecular formula:
C2H3N
IUPAC Name:
acetonitrile
Test material form:
liquid

Results and discussion

Percent distribution in media

Air (%):
13
Water (%):
44.1
Soil (%):
42.8
Sediment (%):
0.08

Any other information on results incl. tables

Estimated Half-life (hrs):

Air - 1544

Water - 360

Soil - 720

Sediment - 3240

Applicant's summary and conclusion

Executive summary:

US EPA EPIWIN software (v3.20) Level III Fugacity Model predicted the following percent distribution and half-lives for acetonitrile in environmental media:

Air - 13%, 1544 hours

Water - 44.1%, 360 hours

Soil - 42.8%, 720 hours

Sediment - 0.0811%, 3240 hours