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Administrative data

Description of key information

To examine probable neuro toxicity  of m-cresol male and femaleCD rats received corn oil solutions of 0, 50, 150, 450 mg/kg bw/day by gavage once daily for 13 weeks. Dose related signs of toxicity and in high dosed rats neurobehavioural signs oftoxicity were reported. The NOAEL is 50 mg/kg bw/day (abstract only, TRL 1986) 

Key value for chemical safety assessment

Additional information

To examine probable neuro toxicity of m-cresol male and femaleCD rats received corn oil solutions of 0, 50, 150, 450 mg/kg bw/day by gavage once daily for 13 weeks. Dose related signs of toxicity and in high dosed rats neurobehavioural signs oftoxicity were reported. The NOAEL is 50 mg/kg bw/day (abstract only, TRL 1986)

Justification for classification or non-classification

no classification is required