Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information


The tropospheric half-life of m-cresol is approximately 6 h due to degradation by OH radicals with an average concentration of 500000 radicals/mL.

With regard to its chemical structure m-cresol is not expected to hydrolyse under environmental conditions.


m-Cresol is readily biodegradable. It is inherent biodegradable, and anaerobically biodegradable. Biodegradation half-lives in 2 agricultural soils were determined to be 0.6 for a sandy loam and 11.3 for a sandy silt loam.


The bioconcentration factor (BCF) in fish (Leuciscus idus melanotus) was determined with 14C-labelled m-cresol. A BCF of 20 was obtained for m-cresol, indicating that the substance is not bioaccumulative.

Adsorption / desorption

The Koc of m-cresol was determined in an experiment, similar to the OECD Guideline 106. A Koc value of 35 was obtained, suggesting a low potential for adsorption.


The experimentally determined Henry's law constant for m-cresol is 0.087 Pa*m³/mole at 25°C. The distribution of m-cresol in a unit world was calculated according to the Mackay fugacity model level I based on its physico-chemical properties. The main target compartment for m-cresol is water with 96.3 %, followed by air with 2 %, soil and sediment each with 0.7 %.