Registration Dossier
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EC number: 203-577-9 | CAS number: 108-39-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
m-Cresol is readily biodegradable under aerobic conditions in freshwater. It is inherently biodegradable, and anaerobically biodegradable
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Serveral experiments on biodegradability are available for m-cresol.
In the aquatic phase, the biodegradability of m-cresol was tested according to OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test). Degradation was 90 % after 28 d and the 10 d window was fulfilled.
In a test according to OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I)), 80 to 95 % of m-cresol was degraded within 40 d. m-Cresol was slightly better biodegradable than phenol and aniline supporting the conclusion that it is readily biodegradable.
m-Cresol is inherently degradable as shown in a test according to the OECD guideline 302 B where 96 % of the added m-cresol was degraded within 10 days after a lag-period of 2 days, and by a similar test, with a removal of 96 % after 5 days of incubation. m- Cresol is also anaerobically biodegradable.
As measured from methane release and carbon dioxide formation, m-cresol is mineralized under methanogenic conditions by anaerobic sludges from wastewater treatment plants. Therefore, m-cresol is considered to be "Readily and Inherently" Biodegradable.
Although the substance is readily biodegradable and no biodegradation simulation test has to be performed for sediments, there are studies available on biodegradation in sediments. m-Cresol is biodegraded in aquifer sediment under anaerobic conditions and by anoxic river sediment within 3-4 weeks.
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