Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-577-9 | CAS number: 108-39-4
Health surveillance data
Administrative data
- Endpoint:
- health surveillance data
- Type of information:
- other: surveillance
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: no data on exposure time
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 008
- Report date:
- 2008
Materials and methods
- Study type:
- health record from industry
- Endpoint addressed:
- repeated dose toxicity: inhalation
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: german Gefahrstoffverordnung §16(2)
- Principles of method if other than guideline:
- occupational medical surveillance
- GLP compliance:
- not specified
Test material
- Reference substance name:
- all isomers: o-cresol, m-cresol, p-cresol
- IUPAC Name:
- all isomers: o-cresol, m-cresol, p-cresol
- Details on test material:
- isomer not specified (no further data)
Constituent 1
Method
- Type of population:
- occupational
- Ethical approval:
- not applicable
- Details on study design:
- medical examination of the staff includes e.g. medical history, physical examination, lung function, ECG/Ergometry, vision testing, audiometry, laboratory examinations of blood and urine
biomonitoring: determination of cresols in urine of workers
Results and discussion
- Results:
- The results of the measurements show that the concentration of cresols in the air on workplaces are low
The maximum cresol concentration from 2003 to 2008 was 0.9 mg/m³. Occupational medical surveillance did not reveal any health effects licke irritaion of the skin, mucosa membranes or upper respiratory tract which could be derived to be from a possible cresol exposure at workplace. Biomonitoring showed that in case of routine handling of cresols with required protection devices cresol concentrations were in all cased below the limiting value.
Any other information on results incl. tables
The results of the measurements show that the concentration of cresols in the air on workplaces fall below the OEL The maximum cresol concentration from 2003 to 2008 was 0.9 mg/m³. Occupational medical surveillance did not reveal any health effects licke irritaion of the skin, mucosa membranes or upper respiratory tract which could be derived to be from a possible cresol exposure at workplace. Biomonitoring showed that in case of routine handling of cresols with required protection devices cresol concentrations were in all cased below the limiting value.
Applicant's summary and conclusion
- Executive summary:
Occupational medical surveillance of a plant in Germany did not report of complaints from irritational effects from workers. The maximal concentration in the air was 0.9 mg/m³ and is regarded to be the NAEC (Currenta 2008).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
