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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to same study
Principles of method if other than guideline:
accumulation of 14C
GLP compliance:
no
Radiolabelling:
yes
Vehicle:
no
Test organisms (species):
Leuciscus idus melanotus
Route of exposure:
aqueous
Test type:
static
Water / sediment media type:
natural water: freshwater
Total exposure / uptake duration:
3 d
Hardness:
100 mg CaO/l
Test temperature:
20-25 °C
pH:
7
Details on test conditions:
5 fish (2-4 g) exposed in closed system
Nominal and measured concentrations:
0.05 mg/l
Reference substance (positive control):
yes
Remarks:
Hexachlorobenzene and several others
Details on estimation of bioconcentration:
concentrations were determined by following radioactivity in fish and water
Type:
BCF
Value:
>= 17 - <= 20
Basis:
whole body w.w.
Calculation basis:
other: after 3 d
Remarks on result:
other: Conc.in environment / dose:0.05 mg/L
Determination of radioactivity includes possible metabolized 
and/or incorporated intermediates
Validity criteria fulfilled:
not specified
Executive summary:

Bioconcentration factors (BCF) in fish (Leuciscus idus melanotus) were determined with 14C-labelled m-cresol. The fish were exposed to a 0.05 mg/l solution of the tests compound. After the test period of 3 days radioactivity was measured in water medium and fish. BCF values of 20 were obtained.

Description of key information

The experimental determined bioconcentration factor (BCF) of m-cresol in fish (Leuciscus idus melanotus) is 20.

Key value for chemical safety assessment

BCF (aquatic species):
20 dimensionless

Additional information

The bioconcentration factor (BCF) in fish (Leuciscus idus melanotus) was determined with 14C-labelled m-cresol. The fish were exposed to a 0.05 mg/l solution of the tests compound. After the test period of 3 days radioactivity was measured in water medium and fish. A BCF value of 20 were obtained.