Registration Dossier

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: conforms to guideline & GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1994
Report Date:
1994

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: OECD 202. Part 2 - effects on biotic systems. 14-d reproduction test
Deviations:
yes
Remarks:
modificated to 21 days
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Analytical purity: 99.7 %

Sampling and analysis

Analytical monitoring:
yes
Details on sampling:
water samples taken from the beginning and the end in 3 intervals

Test organisms

Test organisms (species):
Daphnia magna
Details on test organisms:
Clone 5 (IRChA, France):

Study design

Test type:
semi-static
Water media type:
freshwater
Total exposure duration:
21 d

Test conditions

Test temperature:
20.5 - 21.5 ºC
pH:
8.1 - 8.4
Dissolved oxygen:
8.1 - 9.0 mg/l
Details on test conditions:
Test concentrations: 0 / 0.01 / 0.032 / 0.1 / 0.32 / 1 mg/l (10 animals used per concentration and control group)

Results and discussion

Effect concentrationsopen allclose all
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
0.32 mg/L
Basis for effect:
immobilisation
Duration:
21 d
Dose descriptor:
LOEC
Effect conc.:
1 mg/L
Basis for effect:
immobilisation
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
0.1 mg/L
Basis for effect:
reproduction
Duration:
21 d
Dose descriptor:
LOEC
Effect conc.:
0.32 mg/L
Basis for effect:
reproduction

Applicant's summary and conclusion