Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 807-840-4
CAS number: 64896-70-4
28-day toxicity in the rat by the oral route followed by a 14-day recovery period: NOAEL = 2000 mg/kg bw/d (with the analogous substance DEI)13-week oral toxicity study in the rat including recovery and TK: NOAEL = 2000 mg/kg bw/d (with the analogous substance DEI)
There is no data available on the test
item, but the repeated dose toxicity of DOI was assessed by analogy with
DEI was tested for oral repeated dose
toxicity in rat according to OECD guideline 407 (4 weeks) and according
to OECD 408 (13 weeks). Under the experimental conditions, DEI
administered at the doses of 0.5, 1 and 2 g of DEI/kg for 4 or 13 weeks
did not induce any sign of toxicity. Therefore, the No-Observed-Adverse
Effect Level (NOAEL) of DEI is equal to 2 g of DEI/kg.
with DEI, based on the classification criteria of Annex VI Directive
67/548/EEC or UN/EU GHS, and given the absence of signs of toxicity up
to the highest dose of 2000 mg/kg bw/d administered in rats by gavage
during 4 and 13 weeks, no classification for repeat-dose toxicity is
warranted according to the criteria of Annex VI Directive 67/548/EEC or
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Deze website maakt gebruik van cookies om het surfen zo aangenaam mogelijk te maken.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again