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EC number: 807-840-4 | CAS number: 64896-70-4
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No lethal effect was observed on Danio rerio at the loading rate of 100 mg/L after 96 hours.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 mg/L
Additional information
The acute toxicity on fish of the isosorbide diesters (EC No. 700 -073 -5) has been determined according to the OECD Guideline 203 (semi-static conditions) and in compliance with the GLP.
Due to the very low solubility of the tested substance and its UVCB nature, and in conformity with the Document OCDE N° 23 (Guidance Document on Aquatic Toxicity Testing of Difficult Substances and Mixtures) WAFs were prepared at 1, 10 and 100 mg/L. No mortality was observed on the fish exposed to these different loading rates, therefore the LLO ≥ 100 mg/L (highest tested loading rate)
The substance Isosorbide di-octanoate (CAS No. 64896-70-4 ) was considered to show a LLO ≥ 100 mg/L on the basis of the results obtained in this acute fish test performed with a very similar analogue.
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