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EC number: 807-840-4
CAS number: 64896-70-4
The oral LD50 of DOI is > 2000 mg/kg bw (with no mortality at this dose level).
Acute oral toxicity:
an acute oral toxicity study according to OECD 423, and GLP, scored as
validity 1 according to Klimisch criteria, groups of fasted female
Wistar rats were given a single oral dose of DOI in corn oil at the dose
of 2000 mg/kg bw and observed for 14 days.
the experimental conditions, the oral LD50 of the test item DOI was
higher than 2000 mg/kg in rats.
classification for acute oral toxicity is warranted based on the absence
of mortality up to 2000 mg/kg bw, according to the criteria of Annex VI
Directive 67/548/EEC or UN/EU GHS.
Taking into account these
acceptable data, we can conclude that the test item is not classified as
harmful if swallowed according to CLP criteria.
Acute dermal toxicity:
No data available.
Acute inhalation toxicity:
No data is available.
DOI induces no
mortality in the rat following a single exposure by oral route up to a
limit dose and thus should not to be classified for acute toxicity via
the oral route as defined by the criteria of Annex VI Directive
67/548/EEC or UN/EU GHS classification criteria.
No data are available
by dermal route or by inhalation.
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