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EC number: 807-840-4 | CAS number: 64896-70-4
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No inhibitory effect was observed on the reproduction of Daphnia magna at the concentration of 1 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 1 mg/L
Additional information
The long-term toxicity of the isosorbide diesters (EC No. 700 -073 -5) on the reproduction of Daphnia magna has been determined according to the OECD guideline 211 and in compliance with GLP
The test was performed under semi-static conditions and the daphnids were exposed to the limit concentration of 1 mg/L. All the validity criteria were fullfilled and the exposure concentrations were satisfactory maintained within 80 -120% of the nominal value.
No inhibitory effect was observed on the reproduction of Daphnia magna at the tested concentration of 1 mg/L/
The substance Isosorbide di-octanoate (CAS No. 64896-70-4 ) was considered to show a NOEC ≥ 1 mg/L on the basis of the results obtained in this long-term Daphnia magna reproduction test performed on a very similar analogue.
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