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EC number: 482-020-3
CAS number: -
3,4 Dialdehyde is considered readily biodegradable based on the
following three separate biodegradation studies.
The first study was a Ready Biodegradability Closed Bottle Test – OECD
301D (Desmares-Koopmans, 2006). This study showed that
UNOXOL™ 3,4 Dialdehyde was degraded significantly (54 and 59%, average
56.5%) during the 28-day test period. However, since
60% biodegradation was not reached within 10 days immediately following
the attainment of 10% biodegradation (10 -day window), the strict
criterion for ready biodegradability was not met. Therefore,
under the conditions of this closed bottle test, UNOXOL™ 3,4 Dialdehyde
was not considered to be readily biodegradable.
The second biodegradation study was a Manometric Respirometry Test -
OECD 301F (West and Hales, 2007). The results of this
study indicate that UNOXOL™ 3,4 Dialdehyde did pass the > 60%
biodegradation at Day 28 and the 10-day window criteria for ready
biodegradability. At the end of the 28-day test, the
extent of biodegradation based on biochemical oxygen demand, CO2evolution,
and dissolved organic carbon removal reached 81.6%, 65.2% and 96.7%,
respectively. UNOXOL™ 3,4 Dialdehyde is a mixture of
constitutional and stereo- isomers (cis- and trans- isomers of 1,3-
and 1,4-cyclohexanedicarboxaldehyde) and the extent of degradation
observed in this test indicates that all isomers were fully biodegraded. Under
the conditions of this study and the strict OECD criteria, the UNOXOL™
3,4 Dialdehyde components are readily biodegradable. Thus UNOXOL™ 3,4
Dialdehyde is expected to rapidly and completely biodegrade in a variety
of aerobic environments.
An additional Manometric Respirometry Test (OECD 301F) was recently
completed in China (Jing, 2012) to fulfill the regulatory requirement of
China that biodegradation study needs to be conducted in China. Results
of this study indicate that the mean biodegradation percentage for
UNOXOL™ 3,4 Dialdehyde was 61.4% at day 28 and 53.5% at Day 19 (10-d
window), which does not meet the 10-day window criteria. Therefore,
under the conditions of this study and the strict OECD criteria, UNOXOL™
3,4 Dialdehyde was not considered to be readily biodegradable.
Due to the stringent testing conditions for conducting these types of
biodegradability tests, substances may sometimes fail individual tests
when in reality these substances are readily biodegradable. OECD
guideline Section 3 Introduction states that realizing ready
biodegradability tests may sometimes fail because of the stringent test
conditions, consistent positive test results from other test(s) should
generally supersede negative test results (OECD, 2006).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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