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EC number: 203-545-4
CAS number: 108-05-4
Meiotic micronucleus frequencies in early spermatids of mice 13 days
after a single injection of vinylacetate or acetaldehyde (frequency in
1000 early spermatids)
dose level (mg/kg)
number of mice
frequency (mean± SE)
0.33 ± 0.33
2.25 ± 0.85
2.00 ± 1.08
2.00 ± 0.71
1.00 ± 0.71
1.25 ± 0.48
1.5 ± 0.50
1.57 ± 0.61
4.75** ± 0.75
4.75** ± 3.77
** p<0.01 compared to saline controls
oli = olive oil, cp =cyclophosphamide, sal = saline, adm = adriamycin
Neither vinylacetate nor acetaldehyde (its
metabolite) induced micronuclei in meiotic cells.
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