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Ecotoxicological information

Long-term toxicity to fish

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Description of key information

The NOEC, LOEC and MATC for this study are 0.551, 0.930 and 0.716 mg/L. Recalculated NOEC = 0.16 mg/L.

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater fish:
0.16 mg/L

Additional information

The study by Marino et al., (2003) was carried out in accordance with GLP and recognised test guidelines. The NOEC, LOEC and MATC reported in this study are 0.551, 0.930 and 0.716 mg/L.This result was not based on the Time Weighted Average, recommended in the OECD test guidelines, and therefore the NOEC has been recalculated, using the raw data provided in the report to give a NOEC of 0.16 mg/L. A notable restriction of this study is that the experimenters had difficulty in maintaining the concentration of test substance during the exposure period due in part to the physical and chemical properties of vinyl acetate, and also likely due to a build up of biomass and/or polymerised test material. This has been taken into account when scoring the reliability of this study and assessing whether it can be used.