Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.016 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
0.126 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.002 mg/L
Assessment factor:
100
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
6 mg/L
Assessment factor:
1
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
0.067 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.007 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.004 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

PNECs were derived for freshwater, saltwater, sediment, and soil using either experimental results or equilibrium partitioning calculations. The PNECS derived using experimental data were based on Klimisch 1 or 2 studies because these studies took into account the physico-chemical properties of vinyl acetate and therefore were conducted in closed systems with no or minimal headspace to avoid loss of the test material and ensure a consistent exposure of the organisms. Other studies were available but did not meet the quality criteria and therefore these were not used in the PNEC derivation.

 

QSARs (based on the ecosar class vinyl/allyl esters) were generated using EPI suite, in order to support the use of lower assessment factors for derivation of the PNECs. The QSARs generated reinforce that fish are the most sensitive trophic level.

Conclusion on classification

Based on the criteria of Regulation (EC) No 1272/2008, vinyl acetate has to be classified as “Chronic aquatic toxicity, category 3”, hazard statement H412 “Harmful to aquatic life with long-lasting effects".