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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Link to relevant study record(s)

Reference
Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The data are from an official Japanese data base on experimental data for biodegradation that is well recognised by authorities. The study was performed under standard conditions, but no details on the test are available.
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 305 (Bioconcentration: Flow-through Fish Test)
Deviations:
not specified
GLP compliance:
no
Radiolabelling:
no
Details on sampling:
No data
Details on preparation of test solutions, spiked fish food or sediment:
A dispersant (HCO-40) was used to prepare the test solutions. No additional data available.
Test organisms (species):
Cyprinus carpio
Details on test organisms:
Average lipid content was 5.1 %, no additional data on fish available
Route of exposure:
aqueous
Test type:
flow-through
Water / sediment media type:
natural water: freshwater
Total exposure / uptake duration:
6 wk
Hardness:
No data
Test temperature:
No data
pH:
No data
Dissolved oxygen:
No data
TOC:
No data
Salinity:
No data
Details on test conditions:
No data
Nominal and measured concentrations:
Nominal concentrations were 0.02 and 0.2 %
Reference substance (positive control):
not specified
Details on estimation of bioconcentration:
No data
Lipid content:
5.1 %
Time point:
end of exposure
Type:
BCF
Value:
>= 5.3 - <= 13 dimensionless
Basis:
not specified
Remarks on result:
other: Conc.in environment / dose:0.02 %
Type:
BCF
Value:
>= 5.4 - <= 12 dimensionless
Basis:
not specified
Remarks on result:
other: Conc.in environment / dose:0.2 %
Details on kinetic parameters:
No data
Metabolites:
No data
Results with reference substance (positive control):
No data
Details on results:
No data
Reported statistics:
No data
Validity criteria fulfilled:
yes
Conclusions:
The bioconcentration factor of 1,2,3-trichloropropane in fish ranged from 5.3 to 13.
Executive summary:

The bioconcentration factor of 1,2,3-trichloropropane was tested in accordance with OECD Guideline 305 over six weeks in a continuous flow-through system using carp (Cyprinus carpio). Two levels of 0.02 and 0.2 % were tested. The test solutions were prepared with the dispersant HCO-40. The fish had on average a lipid content of 5.1 %. The bioconcentration factors found at the low dose ranged from 5.3 to 13, and corresponding factors at the high dose ranged from 5.4 to 12.

Description of key information

Key value for chemical safety assessment

BCF (aquatic species):
13 dimensionless

Additional information

The bioconcentration factor of TCP was tested in accordance with OECD Guideline 305 over six weeks in a continuous flow-through system using carp (Cyprinus carpio) (MITI 1992). Two levels of 0.02 and 0.2 % were tested. The test solutions were prepared with the dispersant HCO-40. The fish had on average a lipid content of 5.1 %. The bioconcentration factors found at the low dose ranged from 5.3 to 13, and corresponding factors at the high dose ranged from 5.4 to 12.

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