Registration Dossier
Registration Dossier
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EC number: 260-982-3 | CAS number: 57843-53-5
Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
Description of key information
No exposure of soil is expected from handling and use of N,N,N',N'-tetrakis(2-hydroxypropyl) hexanediamide and thus, no hazards are required to be assessed. The substance is used solely in industrial processes for powder coating, technically required being water-free and applied under closed conditions. Thus, there is no exposure to the environment during use and no additional studies are required.
However, even in case of exceptional exposure such as in a major hazard incidence case, no risk is expected as for the surrogate substance N,N,N',N'-tetrakis(2-hydroxyethyl) hexanediamide absence of toxicity towards three plants (lepidum sativum, brassica rapa and avena sativa) was shown in an OECD 208 study with exposure of 100 mg/kg soil dw. No effects on seedling emergence and following growth has been found up to this concentration and thus, the NOEC for all three plants was 100 mg/kg soil dw.
Key value for chemical safety assessment
- Short-term EC50 or LC50 for terrestrial plants:
- 100 mg/kg soil dw
- Long-term EC10, LC10 or NOEC for terrestrial plants:
- 100 mg/kg soil dw
Additional information
In accordance with Column 2 of REACH, Annexes IX the tests do not need to be conducted if direct and indirect exposure of the substance to soil is unlikely. Thus, no additional test was required for this endpoint.
From the read-across approach, no hazard effect to the seedling emergence and following growth of the three plants has been found up to the concentration of 100 mg/kg dw soil, and it was used as a supporting study.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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