Registration Dossier
Registration Dossier
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EC number: 260-982-3 | CAS number: 57843-53-5
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The EC50 of the Primid QM-1260 is above 100 mg/l based on the nominal concentration, and above 92.2 mg/l based on the measured concentration.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- EC50
- Effect concentration:
- 100 mg/L
Additional information
The median effective concentration (EC50) of Primid QM-1260 to Daphnia magna was investigated under static exposure conditions over a period of 48 h. The only applied nominal test concentration was 100 mg/I. 40 individual Daphnia were divided into 2 test vessels and exposed to the test substance. HPLC analysis of the test substance concentration was performed at the beginning of the test as well as after 24 h and 48 h of incubation. The analysis result revealed that the concentration of Primid QM-1260 remained stable during the test. Time weighted average concentrations of the measured concentrations were calculated to give 92.2 mg/I for 24 and 48 h of exposure.
At the nominal concentration of 100 mg/I no significant effects (i.e. >10% immobilization) were observed after 24 and 48 h of exposure, and there were also no significant effects observed in the control group.
Based on these results the 24 and 48 h EC50 value of Primid QM-1260 is predicted to be >92.2 mg/I after 24 and 48 h of exposure with respect to the time-weighted averages of the measured concentrations.
The no-observed-effect concentration (EC0) for 24 h and 48 h of incubation is above 92.2 mg/I after 24 and 48 h of exposure with respect to the time-weighted averages of the measured concentrations.
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