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EC number: 266-028-2
CAS number: 65996-93-2
The residue from the distillation of high temperature coal tar. A black solid with an approximate softening point from 30°C to 180°C (86°F to 356°F). Composed primarily of a complex mixture of three or more membered condensed ring aromatic hydrocarbons.
Bacterial reverse mutation assays with pitch, coal tar, high-temp.
(CTPht) or surrogates are positive. Other genetic toxicity tests in
vitro with CTPht could not be located. But additional studies are not
necessary, because CTPht is classified as carcinogenic and mutagenic
according to Regulation (EC) No 1272/2008 (including amendments), Annex
VI, Part 3, Table 3.1 (classification Carc. 1A and Muta 1B).
No biologically relevant increases in TA
1535 and TA 102.
Biologically relevant increases in TA 98
(-S9, reproducible) ==> Mutation factor =< 6.6
Biologically relevant increases in TA 98, TA
100, and TA 1537 (+S9) ==> Mutation factor =<24.6 in TA 98
The results may be categorised as follows:
TA 15 - -
TA 1537 - +++ MF = <56
TA 98 + +++ MF = <33
TA 100 -/+ + MF = <5
- = no mutagenic activity
-/+ = not to slightly enhanced
+ = weak but significant
++ = moderate
+++ = strong
MF = mutation factor above solvent control
There was a good correlation between the B[a]P content and
mutagenic activity (Report Fig 1). Coal tar pitch fumes generated at 316
°C contained significantly higher concentrations of PAH than those
generated at 232 °C and the mutagenic activity paralleled the PAH
For pitch, coal tar, high-temp., no information on genetic toxicity in
vivo is available. Additional information is not required, because the
substance is classified as Carc. 1A and Muta. 1B according to Regulation
(EC) No 1272/2008.
Data from Ames-tests only have been provided, since coal-tar pitch
is classified as mutagenic and carcinogenic. In one of the tests, coal
tar pitch (fume condensate) was used as supporting substance.
Pitch, coal tar, high-temp. contains benzo[a]pyrene in
concentrations up to 1.5 %. BaP is known to be mutagenic and is
classified as mutagenic Cat. 1B according to Regulation (EC) No
1272/2008 (CLP regulation). In Ames tests, pitch, coal tar, high-temp.
was demonstrated to be mutagenic. Based on results of the bacterial
reverse mutation assays and of its BaP content, pitch, coal tar,
high-temp. is self-classified by the registrant as mutagenic Cat. 1B in
compliance with Regulation 1272/2008. According to CLP regulation Annex
VI, Part 3, Table 3.1 amended by Commission regulation (EU) No 944/2013,
pitch, coal tar, high-temp. is classified as Muta. 1B.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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