Registration Dossier

Toxicological information

Endpoint summary

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Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

BaP is used as supporting substance to characterise the sensitising potential of pitch, coal tar, high temp. This is justified as BaP is a constituent of coal tar pitch, high temp. at a concentration high enough to cause relevant effects with regard to a sensitive toxicological endpoint such as sensitisation.


Migrated from Short description of key information:
Pitch, coal tar, high temp. is considered to be a potential sensitiser, based on BaP content of 1 - 1.5 %. BaP was shown to be a potent sensitiser in an assay using guinea pig (Old et al. 1963).

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available
Additional information:
Migrated from Short description of key information:
No evidence of a sensitising potential from occupational experience.

Justification for classification or non-classification

Skin Sensitisation

Based on a content of up to 1.5% of benzo(a)pyrene, a strong sensitizer, pitch, coal tar, high-temp., is classified as sensitising Cat. 1 by the registrant.

Respiratory Sensitisation

No experimental data on respiratory sensitisation available. However, based on long-term occupational experience, no classification required.