Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 215-691-6
CAS number: 1344-28-1
The goal of
study is to assess the developmental toxicity and
embryotoxic/teratogenic potential of high doses of target compound -
AI(OH)3orally administered to rats during the period of
significant general/maternal toxicity was observed in any Al treated
groups that were orally exposed to Al hydroxide at doses 66.5, 133 and
266 mg Al/kg bw/day.
have contributed to the weight of evidence on the lack of pre-natal
developmental toxicity of Al hydroxide administered orally to rats at
high doses (66.6; 133 and 266 mg Al/kg bw/day). Toxicokinetic studies
support the reported negative developmental outcomes.
designed and conducted study with many studied endpoints comparable to
guideline OECD TG 414 with acceptable deviations.
particular test data/relevant information are absent (physiochemical
properties, identification including CAS number, details on food and
water quality (Al content in diet, water); details on test substance
formulations (preparation, pH, stability and homogeneity of the
preparation), details on reported negative teratogenic effects are not
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Šajā tīmekļa vietnē tiek izmantoti sīkfaili, lai nodrošinātu Jums vislabāko lietojumu mūsu tīmekļa vietnēs.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again