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Physical & Chemical properties

Water solubility

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Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
Not reported
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Although sufficient experimental details are not provided, the reference is a peer reviewed handbook and is considered reliable with restrictions
Qualifier:
no guideline followed
Principles of method if other than guideline:
Details of the guideline followed to determine the result are not provided.
GLP compliance:
not specified
Type of method:
other: No information available
Water solubility:
0 g/L
Remarks on result:
other: No details on temperature or pH provided.
Details on results:
Insoluble in water

Insoluble

Executive summary:

Aluminium oxide is insoluble in water

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Not reported
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study (OECD 105)
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes
Type of method:
flask method
Water solubility:
<= 0 g/L
Temp.:
20 °C
pH:
ca. 6 - ca. 7

Table 4.3

Sample No. Time shaken at 30 C (hr) Time equilibrated at 20C (hr) Concentration (g/L) pH
1 24 24 ≤ 0.00002 6.8
2 48 24 ≤ 0.00002 6.8
3 72 24 ≤ 0.00002 6.8

mean concentration = 0.00002 g/L at 20 deg C

ICP analysis table from BLL:

BLL ref No. Sample ID Al mg/L
BL-11-0535-09 Sample 1A 0.02
BL-11-0536-09 Sample 1B 0.02
BL-11-0537-09 Sample 2A 0.02
BL-11-0538-09 Sample 2B 0.02
BL-11-0539-09 Sample 3A 0.02
BL-11-0540-09 Sample 3B 0.02
BL-11-0541-09 Blank A 0.02
BL-11-0542-09 Blank B 0.01

Per Appendix 1 page 3 (Walker JA, Butterworth Laboratories, BLL report No 0911-0058):

Reference items: 1000 ppm stock aluminum standard supplied by Romil, Product E3AL6 Lot L546487 and 10000 ppm aluminum stock supplied by Romil, Product N7AL6 Lot E534457

In house method BLM55G issue 17. Discussion of ICP results: instrument was calibrated over range 0.1 to 10 mg/L. A 1 ppm QC check standard was run at the end of the sequence. Results for this standard fell within 95 -105% of target. In-house duplicate tests were not performed as duplicate sampes were prepared prior to receipt. Limit of detection was assessed by preparing a standard at 0.01 mg/L. The readings were made that generated a mean of 0.008 mg/L with a 5% RSD. The theoretical limit of detection was estimated at 0.004 mg/L (10X std dev). Based on this data, a reporting limit of 0.01 mg/L was considered acceptable.

Conclusions:
The water solubility of aluminum oxide as determined by the OECD Guideline 105 was <0.00002 g/L, which is insoluble.
Executive summary:

The water solubility of aluminum oxide was less than or equal to 2x10-5 g/L of solution at 20.0 +/- 0.05 degrees C, withing the pH range 6 to 7 in accordance with the flask method, of the OECD Guidelines for Testing of Chemicals. Aluminum oxide is insoluble.

Description of key information

A weight-of-evidence approach was used to address this endpoint.

Key value for chemical safety assessment

Water solubility:
0 g/L
at the temperature of:
20 °C

Additional information

Data from the key study conducted in 2010, and weight-of-evidence data from prior studies agree that the water solubility of aluminum oxide is very low (0.00002 g/L at 20 °C).