Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 203-398-6 | CAS number: 106-44-5
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: secondary literature
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Effects of phenolic smoke condensates and their components on hepatic drug metabolizing systems
- Author:
- Sternitzke A, Legrum W, Netter KJ
- Year:
- 1 992
- Bibliographic source:
- Fd Chem Toxic 30, 771-781
- Reference Type:
- publication
- Title:
- Ueber die Wirkung der Cresole und des Liquor Cresoli Saponatus im Vergleich zur Carbolsaeure
- Author:
- Tollens K
- Year:
- 1 905
- Bibliographic source:
- Arch Exp Path Pharm 52, 220-241
Materials and methods
- Principles of method if other than guideline:
- other
- GLP compliance:
- not specified
Test material
- Reference substance name:
- p-cresol
- EC Number:
- 203-398-6
- EC Name:
- p-cresol
- Cas Number:
- 106-44-5
- Molecular formula:
- C7H8O
- IUPAC Name:
- p-cresol
- Details on test material:
- Test substance: p-cresol, no further data
Constituent 1
Test animals
- Species:
- mouse
Administration / exposure
- Route of administration:
- subcutaneous
Results and discussion
Effect levels
- Dose descriptor:
- LC50
- Effect level:
- 150 mg/kg bw
Any other information on results incl. tables
no data
Applicant's summary and conclusion
- Executive summary:
Mice received a single subcutaneous injection of p-cresol. A LD50 = 150 mg/kg bw was determined.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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