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Ecotoxicological information

Toxicity to birds

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Description of key information

The available data on avian toxicity cannot be used for assessment due to the insufficient documentation.
In accordance with section 1 of REACH Annex XI, the study does not need to be conducted as avian toxicity data are used in the assessment of secondary poisoning which is required for substances indicating a bioaccumulation potential. p-Cresol has a low potential for bioaccumulation and no adverse effects to birds due to bioaccumulation in food chains would be expected.

Key value for chemical safety assessment

Additional information

No appropriate avian toxicology data are available for p-cresol. Avian toxicity data are used in the assessment of secondary poisoning risks for the aquatic and terrestrial food chains. Secondary poisoning concerns the potential toxic impact of a substance on a predatory bird or mammal following ingestion of prey items (i.e. fish and earthworms) that contain the chemical. Accumulation of chemicals through the food chain may follow many different pathways along different trophic levels. As assessment is solely required for substances for which there is an indication for bioaccumulation potential (ECHA, R.7c, 2008). Bioconcentration factors (BCF) can be used for assessment. Based on the experimental BCF value of the isomer m-cresol indicating no significant potential for bioaccumulation in aquatic organisms, for p-cresol, a similar bioaccumulation behaviour is expected. Furthermore, biodegradability of the substance strongly determines the ability of a substance to bioaccumulate in organisms. As p-cresol is readily biodegradable no risk of bioaccumulation arises. Therefore, based on these properties no adverse effects to birds due to bioaccumulation in food chains would be expected and there is no need for testing.