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Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: in vitro investigation, reliablility of limited relevance

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
An evaluation of the utility of four in vitro short term tests for predicting the cytotoxicity of individual compounds derived from tobacco smoke
Author:
Curvall M et al.,
Year:
1984
Bibliographic source:
Cell Biol Toxicol 1, 173-193 (1984)
Reference Type:
publication
Title:
Effects of tobacco smoke compounds on the cilliary activity of the embryo chicken trachea in vitro. Toxicology 23, 41-55
Author:
Pettersson B et al.,
Year:
1982
Bibliographic source:
Toxicology 23, 41-55 (1982)

Materials and methods

Type of study / information:
Type: other: in vitro

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
migrated dataset

Results and discussion

Any other information on results incl. tables

migrated dataset

Applicant's summary and conclusion

Executive summary:

Ciliostasis within 15 min was observed when 5mM p-cresol was 
added to  embryo chicken trachea in culture.