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EC number: 203-398-6
CAS number: 106-44-5
In an abstract only the examination of probable neurotoxicity of p-cresol was reported:male and female CD rats received conrn oil solutions with 0, 50. 175, 600 mg/kg bw/day p-cresol by gavage once daily for 13 weeks. Dose-related signs of toxicity and in the high dosed rats neurobehavioral signs of toxicity were reported. The NOAEL is 50 mg/kg bw/day (abstract only, TRL 1986).
To examine probable neurotoxicity of p-cresol male and female CD rats
received corn oil solutions with 0, 50. 175, 600 mg/kg bw/day p-cresol
by gvage once daily for 13 weeks. Dose-related signs of toxicity and in
the high dosed rats neurobehavioral signs of toxicity were reported. The
NOAEL is 50 mg/kg bw/day (abstract only, TRL 1986)
no classification is required
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