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EC number: 200-927-2
CAS number: 76-03-9
Weight of evidence: Experimental results on the substance
trichloroacetic acid and read-across from experimental data on the
analogue sodium trichloroacetate.
Trichloroacetic acid was evaluated with the Guinea Pig Maximization Test
(GPMT). None of the test animal showed any irritating or sensitising
symptoms. The test substance resulted to be not sensitising. Results
from a non-guideline compliant test (The Mouse Ear Swelling Test, MEST)
support the negative results obtained with the Guinea Pig Maximization
Test (GPMT) since none of the animals showed any response. The positive
controls included in both experiments showed a 100% response.
Based on company data on the analogue sodium trichloroacetate (OECD
406), which is considered to be not sensitising, and applying the
read-across approach, the substance trichloroacetic acid is also
considered to be not sensitising.
Based on the experimental results, the substance is not classified as
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