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EC number: 200-927-2
CAS number: 76-03-9
Table 07.02.01_01. Doses administered and numbers of fatalities
resulting from each dose.
The acute toxicity was determined for trichloroacetic acid. The mice
used were young adult Albinos of a heterogeneous stock with the sexes
equally distributed. Test solution was administered orally by a straight
metal catheter attached to a syringe. The doses tested were 3162, 3981,
4217, 4467, 4500, 4732, 5012, 5309, 5623 and 6000 mg/kg. Immediately
following the treatment the animals were observed for 6 days. The
dosage-mortality curves are constructed for each substance according to
the methods of Bliss.
The LD50 of trichloroacetic acid for mice was 4970 mg/kg. Depending on
the dosage strength, the experimental animals died between two hours
and, at the least, three days after oral application of lethal doses.
The intoxication symptoms which occurred in mice included ataxia,
sedation, prone and lateral position, diminished food uptake, decreased
capability of triggering reflexes, palsy of the hind extremities and
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