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EC number: 200-927-2
CAS number: 76-03-9
In the present study, data from several years of birth certificate data
were used to examine the relationship between indices of fetal
development and various town averate exposure metrics. Data from
1997-1998 on haloacetic acid (total haloacetic acids, dichloroacetic
acid and trichloroacetic acid) were available for limited number of
Birth weight: No associations were detected for high third-trimester
haloaceti acids exposures, but birth weight increases > 20 g were
observed for intermediate total haloacetic and trichloroacetic acids.
Gestational age: Trichloroacetic acid > 27 μg/L was associated with
shorter gestational duration (–0.9 days; 95% CI, –1.7 to –0.1) compared
with ≤ 18 μg/L.
Small for gestational age (SGA) infancy: We did not detect an increased
risk of SGA infancy for high haloacetic acid exposures, but inverse
associations were detected for intermediate trichloroacetic and
dichloroacetic acid exposures.
Preterm delivery: an increased risk was observed for high
trichloroacetic (OR = 1.33; 95% CI, 0.77 to 2.30) and total HAAs (OR =
1.48; 95% CI, 0.84 to 2.61).
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